PT-141 (Bremelanotide): molecular Formula C50H68N14O10. buy PT-141 (Bremelanotide) online 10mg vial. Buy PT-141 cheap price, PT-141 is a synthetic peptide.
What is PT-141 bremelanotide 10mg vials lyopgilized powder
Bremelanotide , once in the past known as PT-141, is a peptide medication which is (or has) been a work in progress by Palatin Technologies as a treatment for female sexual brokenness (FSD), hemorrhagic stun, and reperfusion harm. Bremelanotide was initially tried for intranasal organization in treating FSD yet this application was briefly stopped in 2008 after concerns were raised over expanded pulse seen with bremelanotide organization in a few patients. As of December 2014, Palatin is leading a human stage III study[2] utilizing a subcutaneous medication conveyance framework that seems to have little impact on circulatory strain.
Structure of PT-141
Bremelanotide is a cyclic heptapeptide lactam simple of α-melanocyte-invigorating hormone (α-MSH). It has the amino corrosive arrangement Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH, and is otherwise called cyclo-[Nle4,Asp5,D-Phe7,Lys10]α-MSH-(4-10). Bremelanotide is a dynamic metabolite of melanotan II that does not have the C-terminal amide group.
Pharmacology for PT-141
Bremelanotide, comparably to its analogs α-MSH and melanotan II, goes about as a non-specific agonist of the greater part of the melanocortin receptors aside from MC2, where it needs critical liking
Bremelanotide seems to fortify sexual longing and excitement totally or for the most part by means of actuation of the MC4 receptor (the MC3 receptor might likewise be included). It regulates aggravation and breaking points ischemia by means of actuation of the MC1 and MC4 receptors
As indicated by Palatin Technologies' unique 2003 patent for bremelanotide, it has more or less 50 times the power of melanotan II as an inducer of erection in male rats. likewise, it was expressed in the patent that the helpful window of bremelanotide in creatures (particularly, the scope of impelling of the craved sexual excitement in respect to the instigation of symptoms including queasiness, yawning, extending, and diminished hankering) was >1,000-fold, while that of melanotan II was just 3-to 4-fold. They presumed that bremelanotide would be more fair than melanotan II.[13] However, in human clinical trials, bremelanotide has, comparatively to melanotan II, been found to create sickness and spewing (however yawning, extending, and loss of longing don't appear to have been reported).Other symptoms reported for bremelanotide in human clinical trials incorporate transient facial flushing, sweating, sluggishness, cerebral pain, unsteadiness, dysgeusia (modified feeling of taste), hypertension, and skin hyperpigmentation.
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CAUTION:
This product is NOT intended to prevent, treat, or cure disease conditions or to affect the structure or function of the body. The sale of this product is restricted to research applications ONLY. This product is NOT for human consumption. This product can be harmful if ingested. Picture may differ from actual product.
